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Lipid Raft-Mediated Regulation of G-Protein Coupled Receptor Signaling by Ligands which Influence Receptor Dimerization: A Computational Study
G-protein coupled receptors (GPCRs) are the largest family of cell surface receptors; they activate heterotrimeric G-proteins in response to ligand stimulation. Although many GPCRs have been shown to form homo- and/or heterodimers on the cell membrane, the purpose of this dimerization is not known....
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719103/ https://www.ncbi.nlm.nih.gov/pubmed/19668374 http://dx.doi.org/10.1371/journal.pone.0006604 |