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Recognition of atypical 5' splice sites by shifted base-pairing to U1 snRNA
Accurate pre-mRNA splicing is critical for gene expression. The 5' splice site (5' ss) — the highly diverse element at the 5' end of introns — is initially recognized via base-pairing to the 5' end of U1 small nuclear RNA (snRNA). However, many natural 5' ss have a very poor...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719486/ https://www.ncbi.nlm.nih.gov/pubmed/19169258 http://dx.doi.org/10.1038/nsmb.1546 |