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Hippocampal Atrophy as a Quantitative Trait in a Genome-Wide Association Study Identifying Novel Susceptibility Genes for Alzheimer's Disease

BACKGROUND: With the exception of APOE ε4 allele, the common genetic risk factors for sporadic Alzheimer's Disease (AD) are unknown. METHODS AND FINDINGS: We completed a genome-wide association study on 381 participants in the ADNI (Alzheimer's Disease Neuroimaging Initiative) study. Sampl...

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Detalles Bibliográficos
Autores principales: Potkin, Steven G., Guffanti, Guia, Lakatos, Anita, Turner, Jessica A., Kruggel, Frithjof, Fallon, James H., Saykin, Andrew J., Orro, Alessandro, Lupoli, Sara, Salvi, Erika, Weiner, Michael, Macciardi, Fabio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719581/
https://www.ncbi.nlm.nih.gov/pubmed/19668339
http://dx.doi.org/10.1371/journal.pone.0006501