An exploration of the ability of tepoxalin to ameliorate the degradation of articular cartilage in a canine in vitro model

BACKGROUND: To study the ability of tepoxalin, a dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX) and its active metabolite to reduce the catabolic response of cartilage to cytokine stimulation in an in vitro model of canine osteoarthritis (OA). Grossly normal cartilage was collected po...

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Detalles Bibliográficos
Autores principales: Macrory, Lisa, Vaughan-Thomas, Anne, Clegg, Peter D, Innes, John F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719625/
https://www.ncbi.nlm.nih.gov/pubmed/19624842
http://dx.doi.org/10.1186/1746-6148-5-25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719625/
https://www.ncbi.nlm.nih.gov/pubmed/19624842
http://dx.doi.org/10.1186/1746-6148-5-25

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