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An exploration of the ability of tepoxalin to ameliorate the degradation of articular cartilage in a canine in vitro model
BACKGROUND: To study the ability of tepoxalin, a dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX) and its active metabolite to reduce the catabolic response of cartilage to cytokine stimulation in an in vitro model of canine osteoarthritis (OA). Grossly normal cartilage was collected po...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719625/ https://www.ncbi.nlm.nih.gov/pubmed/19624842 http://dx.doi.org/10.1186/1746-6148-5-25 |