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Neuropilin-2 expression in breast cancer: correlation with lymph node metastasis, poor prognosis, and regulation of CXCR4 expression

BACKGROUND: Neuropilin-2 (Nrp2) is a receptor for vascular endothelial growth factor-C (VEGF-C), which is a well-known lymphangiogenic factor and plays an important role in lymph node metastasis of various human cancers, including breast cancer. Recently, Nrp2 was shown to play a role in cancer by p...

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Detalles Bibliográficos
Autores principales: Yasuoka, Hironao, Kodama, Rieko, Tsujimoto, Masahiko, Yoshidome, Katsuhide, Akamatsu, Hiroki, Nakahara, Masaaki, Inagaki, Michiya, Sanke, Tokio, Nakamura, Yasushi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719661/
https://www.ncbi.nlm.nih.gov/pubmed/19580679
http://dx.doi.org/10.1186/1471-2407-9-220