RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression

BACKGROUND: RIZ1 expression and activity are reduced in many cancers. In AML cell lines and patient material, RIZ1 expression is reduced relative to normal bone marrow. In chronic myelogenous leukemia (CML), blastic transformation is associated with loss of heterozygosity in the region where RIZ1 is...

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Detalles Bibliográficos
Autores principales: Lakshmikuttyamma, Ashakumary, Takahashi, Naoto, Pastural, Elodie, Torlakovic, Emina, Amin, Hesham M, Garcia-Manero, Guillermo, Voralia, Michael, Czader, Magdalena, DeCoteau, John F, Geyer, C Ronald
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719666/
https://www.ncbi.nlm.nih.gov/pubmed/19602237
http://dx.doi.org/10.1186/1756-8722-2-28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719666/
https://www.ncbi.nlm.nih.gov/pubmed/19602237
http://dx.doi.org/10.1186/1756-8722-2-28

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