The mycobacterial glycolipid glucose monomycolate induces a memory T cell response comparable to a model protein antigen and no B cell response upon experimental vaccination of cattle

Glycolipids are presented to T cells by human group 1 CD1 proteins, but are not used as subunit vaccines yet. Experimental immunizations with pure mycobacterial glucose monomycolate (GMM) and keyhole limpet haemocyanin (KLH) in cattle, a species which, unlike mice, expresses group 1 CD1, showed that...

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Detalles Bibliográficos
Autores principales: Nguyen, Thi Kim Anh, Koets, Ad P., Santema, Wiebren J., van Eden, Willem, Rutten, Victor P.M.G., Van Rhijn, Ildiko
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719691/
https://www.ncbi.nlm.nih.gov/pubmed/19538998
http://dx.doi.org/10.1016/j.vaccine.2009.05.078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719691/
https://www.ncbi.nlm.nih.gov/pubmed/19538998
http://dx.doi.org/10.1016/j.vaccine.2009.05.078

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