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The mycobacterial glycolipid glucose monomycolate induces a memory T cell response comparable to a model protein antigen and no B cell response upon experimental vaccination of cattle
Glycolipids are presented to T cells by human group 1 CD1 proteins, but are not used as subunit vaccines yet. Experimental immunizations with pure mycobacterial glucose monomycolate (GMM) and keyhole limpet haemocyanin (KLH) in cattle, a species which, unlike mice, expresses group 1 CD1, showed that...
Autores principales: | Nguyen, Thi Kim Anh, Koets, Ad P., Santema, Wiebren J., van Eden, Willem, Rutten, Victor P.M.G., Van Rhijn, Ildiko |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719691/ https://www.ncbi.nlm.nih.gov/pubmed/19538998 http://dx.doi.org/10.1016/j.vaccine.2009.05.078 |
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