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The Carboxyl Terminus of Brca2 Links the Disassembly of Rad51 Complexes to Mitotic Entry

BACKGROUND: The Rad51 recombinase assembles on DNA to execute homologous DNA recombination (HR). This process is essential to repair replication-associated genomic lesions before cells enter mitosis, but how it is started and stopped during the cell cycle remains poorly understood. Rad51 assembly is...

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Detalles Bibliográficos
Autores principales: Ayoub, Nabieh, Rajendra, Eeson, Su, Xinyi, Jeyasekharan, Anand D., Mahen, Robert, Venkitaraman, Ashok R.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719694/
https://www.ncbi.nlm.nih.gov/pubmed/19540122
http://dx.doi.org/10.1016/j.cub.2009.05.057