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The Role of Transporters in the Pharmacokinetics of Orally Administered Drugs

Drug transporters are recognized as key players in the processes of drug absorption, distribution, metabolism, and elimination. The localization of uptake and efflux transporters in organs responsible for drug biotransformation and excretion gives transporter proteins a unique gatekeeper function in...

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Detalles Bibliográficos
Autores principales: Shugarts, Sarah, Benet, Leslie Z.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719753/
https://www.ncbi.nlm.nih.gov/pubmed/19568696
http://dx.doi.org/10.1007/s11095-009-9924-0