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A dual mechanism of cytoprotection afforded by M-LDH in embryonic heart H9C2 cells

Muscle form of lactate dehydrogenase (M-LDH), a minor LDH form in cardiomyocytes, physically interacts with ATP-sensitive K(+) (K(ATP)) channel-forming subunits. Here, we have shown that expression of 193gly-M-LDH, an inactive mutant of M-LDH, inhibit regulation of the K(ATP) channels activity by LD...

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Detalles Bibliográficos
Autores principales: Jovanović, Sofija, Du, Qingyou, Sukhodub, Andriy, Jovanović, Aleksandar
Formato: Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719797/
https://www.ncbi.nlm.nih.gov/pubmed/19406174
http://dx.doi.org/10.1016/j.bbamcr.2009.04.007