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A dual mechanism of cytoprotection afforded by M-LDH in embryonic heart H9C2 cells
Muscle form of lactate dehydrogenase (M-LDH), a minor LDH form in cardiomyocytes, physically interacts with ATP-sensitive K(+) (K(ATP)) channel-forming subunits. Here, we have shown that expression of 193gly-M-LDH, an inactive mutant of M-LDH, inhibit regulation of the K(ATP) channels activity by LD...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Pub. Co
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719797/ https://www.ncbi.nlm.nih.gov/pubmed/19406174 http://dx.doi.org/10.1016/j.bbamcr.2009.04.007 |