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Calpain-10 Expression Is Elevated in Pancreatic Islets from Patients with Type 2 Diabetes
BACKGROUND: Calpain-10 was the first gene to be identified influencing the risk of type 2 diabetes (T2D) by positioning cloning. Studies in β-cell lines and rodent islets suggest that calpain-10 may act as a regulator of insulin secretion. However, its role in human pancreatic islets remains unclear...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719809/ https://www.ncbi.nlm.nih.gov/pubmed/19688040 http://dx.doi.org/10.1371/journal.pone.0006558 |