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Calpain-10 Expression Is Elevated in Pancreatic Islets from Patients with Type 2 Diabetes

BACKGROUND: Calpain-10 was the first gene to be identified influencing the risk of type 2 diabetes (T2D) by positioning cloning. Studies in β-cell lines and rodent islets suggest that calpain-10 may act as a regulator of insulin secretion. However, its role in human pancreatic islets remains unclear...

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Detalles Bibliográficos
Autores principales:	Ling, Charlotte, Groop, Leif, Guerra, Silvia Del, Lupi, Roberto
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719809/ https://www.ncbi.nlm.nih.gov/pubmed/19688040 http://dx.doi.org/10.1371/journal.pone.0006558

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