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Tissue Effect on Genetic Control of Transcript Isoform Variation

Current genome-wide association studies (GWAS) are moving towards the use of large cohorts of primary cell lines to study a disease of interest and to assign biological relevance to the genetic signals identified. Here, we use a panel of human osteoblasts (HObs) to carry out a transcriptomic survey,...

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Detalles Bibliográficos
Autores principales: Kwan, Tony, Grundberg, Elin, Koka, Vonda, Ge, Bing, Lam, Kevin C. L., Dias, Christel, Kindmark, Andreas, Mallmin, Hans, Ljunggren, Östen, Rivadeneira, Fernando, Estrada, Karol, van Meurs, Joyce B., Uitterlinden, Andre, Karlsson, Magnus, Ohlsson, Claes, Mellström, Dan, Nilsson, Olle, Pastinen, Tomi, Majewski, Jacek
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719916/
https://www.ncbi.nlm.nih.gov/pubmed/19680542
http://dx.doi.org/10.1371/journal.pgen.1000608