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Effector-memory T cell responses are associated with protection of rhesus monkeys from mucosal SIV challenge
The rapid onset of massive, systemic viral replication during primary HIV/SIV infection and the immune evasion capabilities of these viruses pose fundamental problems for vaccines that depend upon initial viral replication to stimulate effector T cell expansion and differentiation1–5. We hypothesize...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720091/ https://www.ncbi.nlm.nih.gov/pubmed/19219024 http://dx.doi.org/10.1038/nm.1935 |