Effector-memory T cell responses are associated with protection of rhesus monkeys from mucosal SIV challenge

The rapid onset of massive, systemic viral replication during primary HIV/SIV infection and the immune evasion capabilities of these viruses pose fundamental problems for vaccines that depend upon initial viral replication to stimulate effector T cell expansion and differentiation1–5. We hypothesize...

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Detalles Bibliográficos
Autores principales: Hansen, Scott G., Vieville, Cassandra, Whizin, Nathan, Coyne-Johnson, Lia, Siess, Don C., Drummond, Derek D., Legasse, Alfred W., Axthelm, Michael K., Oswald, Kelli, Trubey, Charles M., Piatak, Michael, Lifson, Jeffrey D., Nelson, Jay A., Jarvis, Michael A., Picker, Louis J.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720091/
https://www.ncbi.nlm.nih.gov/pubmed/19219024
http://dx.doi.org/10.1038/nm.1935

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