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Type I collagen inhibits differentiation and promotes a stem cell-like phenotype in human colorectal carcinoma cells
BACKGROUND: Human colorectal cancer is caused by mutations and is thought to be maintained by a population of cancer stem cells. Further phenotypic changes occurring at the invasive edge suggest that colon cancer cells are also regulated by their microenvironment. Type I collagen, a promoter of the...
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| Formato: | Texto |
| Lenguaje: | English |
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Nature Publishing Group
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720218/ https://www.ncbi.nlm.nih.gov/pubmed/19568234 http://dx.doi.org/10.1038/sj.bjc.6605143 |