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Newly characterised ex vivo colospheres as a three-dimensional colon cancer cell model of tumour aggressiveness

BACKGROUND: New models continue to be required to improve our understanding of colorectal cancer progression. To this aim, we characterised in this study a three-dimensional multicellular tumour model that we named colospheres, directly obtained from mechanically dissociated colonic primary tumours...

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Detalles Bibliográficos
Autores principales: Weiswald, L-B, Richon, S, Validire, P, Briffod, M, Lai-Kuen, R, Cordelières, F P, Bertrand, F, Dargere, D, Massonnet, G, Marangoni, E, Gayet, B, Pocard, M, Bieche, I, Poupon, M-F, Bellet, D, Dangles-Marie, V
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720229/
https://www.ncbi.nlm.nih.gov/pubmed/19603013
http://dx.doi.org/10.1038/sj.bjc.6605173