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Newly characterised ex vivo colospheres as a three-dimensional colon cancer cell model of tumour aggressiveness
BACKGROUND: New models continue to be required to improve our understanding of colorectal cancer progression. To this aim, we characterised in this study a three-dimensional multicellular tumour model that we named colospheres, directly obtained from mechanically dissociated colonic primary tumours...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720229/ https://www.ncbi.nlm.nih.gov/pubmed/19603013 http://dx.doi.org/10.1038/sj.bjc.6605173 |