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A study of pyrimidine base damage in relation to oxidative stress and cancer

BACKGROUND: A long-standing hypothesis is that oxidative stress is a risk factor for cancer. Support for this hypothesis comes from observations of higher levels of oxidative damage in the DNA of WBC of cancer patients compared with healthy controls. METHODS: Two generally overlooked types of DNA da...

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Detalles Bibliográficos
Autores principales: Iijima, H, Patrzyc, H B, Budzinski, E E, Freund, H G, Dawidzik, J B, Rodabaugh, K J, Box, H C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720235/
https://www.ncbi.nlm.nih.gov/pubmed/19603029
http://dx.doi.org/10.1038/sj.bjc.6605176