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Increased expression of ALCAM/CD166 in pancreatic cancer is an independent prognostic marker for poor survival and early tumour relapse

BACKGROUND: ALCAM (activated leucocyte cell adhesion molecule, synonym CD166) is a cell adhesion molecule, which belongs to the Ig superfamily. Disruption of the ALCAM-mediated adhesiveness by proteolytic sheddases such as ADAM17 has been suggested to have a relevant impact on tumour invasion. Altho...

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Detalles Bibliográficos
Autores principales: Kahlert, C, Weber, H, Mogler, C, Bergmann, F, Schirmacher, P, Kenngott, H G, Matterne, U, Mollberg, N, Rahbari, N N, Hinz, U, Koch, M, Aigner, M, Weitz, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720248/
https://www.ncbi.nlm.nih.gov/pubmed/19603023
http://dx.doi.org/10.1038/sj.bjc.6605136