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Genome-Wide Screen of Genes Required for Caffeine Tolerance in Fission Yeast

BACKGROUND: An excess of caffeine is cytotoxic to all eukaryotic cell types. We aim to study how cells become tolerant to a toxic dose of this drug, and the relationship between caffeine and oxidative stress pathways. METHODOLOGY/PRINCIPAL FINDINGS: We searched for Schizosaccharomyces pombe mutants...

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Detalles Bibliográficos
Autores principales: Calvo, Isabel A., Gabrielli, Natalia, Iglesias-Baena, Iván, García-Santamarina, Sarela, Hoe, Kwang-Lae, Kim, Dong Uk, Sansó, Miriam, Zuin, Alice, Pérez, Pilar, Ayté, José, Hidalgo, Elena
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720375/
https://www.ncbi.nlm.nih.gov/pubmed/19672306
http://dx.doi.org/10.1371/journal.pone.0006619