Histone levels are regulated by phosphorylation and ubiquitylation dependent proteolysis

Histone levels are tightly regulated to prevent harmful effects such as genomic instability and hypersensitivity to DNA damaging agents due to the accumulation of these highly basic proteins when DNA replication slows down or stops. Although chromosomal histones are stable, excess (non-chromatin bou...

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Detalles Bibliográficos
Autores principales: Singh, Rakesh Kumar, Kabbaj, Marie-Helene Miquel, Paik, Johanna, Gunjan, Akash
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720428/
https://www.ncbi.nlm.nih.gov/pubmed/19578373
http://dx.doi.org/10.1038/ncb1903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720428/
https://www.ncbi.nlm.nih.gov/pubmed/19578373
http://dx.doi.org/10.1038/ncb1903

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