The Wnt Receptor, Lrp5, Is Expressed by Mouse Mammary Stem Cells and Is Required to Maintain the Basal Lineage

BACKGROUND: Ectopic Wnt signaling induces increased stem/progenitor cell activity in the mouse mammary gland, followed by tumor development. The Wnt signaling receptors, Lrp5/6, are uniquely required for canonical Wnt activity. Previous data has shown that the absence of Lrp5 confers resistance to W...

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Detalles Bibliográficos
Autores principales: Badders, Nisha M., Goel, Shruti, Clark, Rod J., Klos, Kristine S., Kim, Soyoung, Bafico, Anna, Lindvall, Charlotta, Williams, Bart O., Alexander, Caroline M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720450/
https://www.ncbi.nlm.nih.gov/pubmed/19672307
http://dx.doi.org/10.1371/journal.pone.0006594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720450/
https://www.ncbi.nlm.nih.gov/pubmed/19672307
http://dx.doi.org/10.1371/journal.pone.0006594

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