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Converging Pharmacological and Genetic Evidence Indicates a Role for Steroid Sulfatase in Attention

BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is a complex neurodevelopmental disorder characterized by deficits in attention, increased motor impulsivity, and hyperactivity. Preliminary work in mice and humans has suggested the X-linked gene STS (which encodes the enzyme steroid sulfa...

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Detalles Bibliográficos
Autores principales: Davies, William, Humby, Trevor, Kong, Wendy, Otter, Tamara, Burgoyne, Paul S., Wilkinson, Lawrence S.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720459/
https://www.ncbi.nlm.nih.gov/pubmed/19251250
http://dx.doi.org/10.1016/j.biopsych.2009.01.001