Bax-Induced Apoptosis in Leber's Congenital Amaurosis: A Dual Role in Rod and Cone Degeneration

Pathogenesis in the Rpe65(−/−) mouse model of Leber's congenital amaurosis (LCA) is characterized by a slow and progressive degeneration of the rod photoreceptors. On the opposite, cones degenerate rapidly at early ages. Retinal degeneration in Rpe65 (−/−) mice, showing a null mutation in the g...

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Detalles Bibliográficos
Autores principales: Hamann, Séverine, Schorderet, Daniel F., Cottet, Sandra
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720534/
https://www.ncbi.nlm.nih.gov/pubmed/19672311
http://dx.doi.org/10.1371/journal.pone.0006616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720534/
https://www.ncbi.nlm.nih.gov/pubmed/19672311
http://dx.doi.org/10.1371/journal.pone.0006616

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