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Enhanced susceptibility of cyclin kinase inhibitor p21 knockout mice to high fat diet induced atherosclerosis
Cyclin kinase inhibitor p21 is one of the most potent inhibitors of aortic smooth muscle cell proliferation, a key mediator of atherosclerosis. This study tests if p2l deficiency will result in severe atherosclerosis in a mouse model. p21(-/- )and strain matched wild type mice were fed with high fat...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720941/ https://www.ncbi.nlm.nih.gov/pubmed/19604372 http://dx.doi.org/10.1186/1423-0127-16-66 |