Cargando…

DNA damage induces nuclear translocation of parkin

Parkinson's disease (PD) is the second most common form of human degenerative disorder. Mutation of parkin is one of the most prevalent causes of autosomal recessive PD. Parkin is an E3 ubiquitin ligase that acts on a variety of substrates, resulting in polyubiquitination and degradation by the...

Descripción completa

Detalles Bibliográficos
Autor principal: Kao, Shyan-Yuan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720942/
https://www.ncbi.nlm.nih.gov/pubmed/19615059
http://dx.doi.org/10.1186/1423-0127-16-67