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DNA damage induces nuclear translocation of parkin
Parkinson's disease (PD) is the second most common form of human degenerative disorder. Mutation of parkin is one of the most prevalent causes of autosomal recessive PD. Parkin is an E3 ubiquitin ligase that acts on a variety of substrates, resulting in polyubiquitination and degradation by the...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720942/ https://www.ncbi.nlm.nih.gov/pubmed/19615059 http://dx.doi.org/10.1186/1423-0127-16-67 |