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Death of a tumor: targeting CCN in pancreatic cancer
The matricellular protein CCN2 (connective tissue growth factor, CTGF) has been previously implicated in tumorigenesis. In pancreatic cancer cells, CCN2 expression occurs downstream of ras/MEK/ERK. Direct evidence that CCN2 mediates tumor progression in pancreatic cancer has been lacking. An excitin...
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| Formato: | Texto |
| Lenguaje: | English |
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Springer Netherlands
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721081/ https://www.ncbi.nlm.nih.gov/pubmed/19267221 http://dx.doi.org/10.1007/s12079-009-0042-x |