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Yin and Yang: CCN3 inhibits the pro-fibrotic effects of CCN2
Fibrotic disease is a significant cause of mortality. CCN2 (connective tissue growth factor [CTGF]), a member of the CCN family of matricellular proteins, plays a significant role in driving the fibrogenic effects of cytokines such as transforming growth factor β (TGFβ). It has been proposed that ot...
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Formato: | Texto |
Lenguaje: | English |
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Springer Netherlands
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721085/ https://www.ncbi.nlm.nih.gov/pubmed/19475498 http://dx.doi.org/10.1007/s12079-009-0056-4 |