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Review of erlotinib in the treatment of advanced non-small cell lung cancer

Epidermal growth factor receptor (EGFR) is a transmembrane receptor with a cytoplasmic tyrosine kinase (TK) domain present on many solid tumors including non-small cell lung cancer (NSCLC). Once stimulated by ligand, the downstream pathway is activated leading to cell growth, survival, and carcinoge...

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Detalles Bibliográficos
Autores principales: Ganjoo, Kristen N, Wakelee, Heather
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721286/
https://www.ncbi.nlm.nih.gov/pubmed/19707304