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Lepirudin in the management of patients with heparin-induced thrombocytopenia

Lepirudin, a recombinant hirudin, is a direct irreversible thrombin inhibitor by binding to both free and clot-bound thrombin. It is approved for treatment of heparin-induced thrombocytopenia (HIT), which is a serious antibody-mediated drug reaction mostly associated with the use of unfractionated h...

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Detalles Bibliográficos
Autor principal: Petros, Sirak
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721403/
https://www.ncbi.nlm.nih.gov/pubmed/19707378