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Lepirudin in the management of patients with heparin-induced thrombocytopenia
Lepirudin, a recombinant hirudin, is a direct irreversible thrombin inhibitor by binding to both free and clot-bound thrombin. It is approved for treatment of heparin-induced thrombocytopenia (HIT), which is a serious antibody-mediated drug reaction mostly associated with the use of unfractionated h...
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| Formato: | Texto |
| Lenguaje: | English |
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Dove Medical Press
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721403/ https://www.ncbi.nlm.nih.gov/pubmed/19707378 |