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A Computational Screen for Regulators of Oxidative Phosphorylation Implicates SLIRP in Mitochondrial RNA Homeostasis

The human oxidative phosphorylation (OxPhos) system consists of approximately 90 proteins encoded by nuclear and mitochondrial genomes and serves as the primary cellular pathway for ATP biosynthesis. While the core protein machinery for OxPhos is well characterized, many of its assembly, maturation,...

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Detalles Bibliográficos
Autores principales: Baughman, Joshua M., Nilsson, Roland, Gohil, Vishal M., Arlow, Daniel H., Gauhar, Zareen, Mootha, Vamsi K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721412/
https://www.ncbi.nlm.nih.gov/pubmed/19680543
http://dx.doi.org/10.1371/journal.pgen.1000590