Osteo-Chondroprogenitor–Specific Deletion of the Selenocysteine tRNA Gene, Trsp, Leads to Chondronecrosis and Abnormal Skeletal Development: A Putative Model for Kashin-Beck Disease

Kashin-Beck disease, a syndrome characterized by short stature, skeletal deformities, and arthropathy of multiple joints, is highly prevalent in specific regions of Asia. The disease has been postulated to result from a combination of different environmental factors, including contamination of barle...

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Detalles Bibliográficos
Autores principales: Downey, Charlene M., Horton, Chelsea R., Carlson, Bradley A., Parsons, Trish E., Hatfield, Dolph L., Hallgrímsson, Benedikt, Jirik, Frank R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721633/
https://www.ncbi.nlm.nih.gov/pubmed/19696890
http://dx.doi.org/10.1371/journal.pgen.1000616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721633/
https://www.ncbi.nlm.nih.gov/pubmed/19696890
http://dx.doi.org/10.1371/journal.pgen.1000616

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