Cargando…

Osteo-Chondroprogenitor–Specific Deletion of the Selenocysteine tRNA Gene, Trsp, Leads to Chondronecrosis and Abnormal Skeletal Development: A Putative Model for Kashin-Beck Disease

Kashin-Beck disease, a syndrome characterized by short stature, skeletal deformities, and arthropathy of multiple joints, is highly prevalent in specific regions of Asia. The disease has been postulated to result from a combination of different environmental factors, including contamination of barle...

Descripción completa

Detalles Bibliográficos
Autores principales:	Downey, Charlene M., Horton, Chelsea R., Carlson, Bradley A., Parsons, Trish E., Hatfield, Dolph L., Hallgrímsson, Benedikt, Jirik, Frank R.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721633/ https://www.ncbi.nlm.nih.gov/pubmed/19696890 http://dx.doi.org/10.1371/journal.pgen.1000616

Ejemplares similares

Biosynthesis of Selenocysteine on Its tRNA in Eukaryotes
por: Xu, Xue-Ming, et al.
Publicado: (2007)

Kashin-Beck disease involving the ankles
por: Niebulski, Hannah Z., et al.
Publicado: (2015)

Proteoglycan metabolism, cell death and Kashin-Beck Disease
por: Li, Siyuan, et al.
Publicado: (2012)

Growth surveillance indices and Kashin-Beck Disease in children
por: 马玮娟 (Ma Wei Juan),
Publicado: (2022)

Mouse Models Targeting Selenocysteine tRNA Expression for Elucidating the Role of Selenoproteins in Health and Development
por: Carlson, Bradley A., et al.
Publicado: (2009)

Prevalence of hand osteoarthritis and knee osteoarthritis in Kashin-Beck disease endemic areas and non Kashin-Beck disease endemic areas: A status survey
por: Lian, Wei, et al.
Publicado: (2018)

Detection of selenoprotein transcriptome in chondrocytes of patients with Kashin–Beck disease
por: Gong, Yi, et al.
Publicado: (2023)

TRSP is dispensable for the Plasmodium pre-erythrocytic phase
por: Costa, David Mendes, et al.
Publicado: (2018)

The role of humic substances in drinking water in Kashin-Beck disease in China.
por: Peng, A, et al.
Publicado: (1999)

Whole-Exome Sequencing for the Identification of Susceptibility Genes of Kashin–Beck Disease
por: Yang, Zhenxing, et al.
Publicado: (2014)

Identifying discriminative features for diagnosis of Kashin-Beck disease among adolescents
por: Zhang, Yanan, et al.
Publicado: (2021)

A study on atypical Kashin–Beck disease: an endemic ankle arthritis
por: Qi, Fang, et al.
Publicado: (2023)

Regulation of Selenocysteine Content of Human Selenoprotein P by Dietary Selenium and Insertion of Cysteine in Place of Selenocysteine
por: Turanov, Anton A., et al.
Publicado: (2015)

Arthroscopic Ankle Arthrodesis for Treating Osteoarthritis in a Patient with Kashin-Beck Disease
por: Iwasa, Kenjiro, et al.
Publicado: (2014)

Genetic variants in the ITPR2 gene are associated with Kashin‐Beck Disease in Tibetan
por: He, Xue, et al.
Publicado: (2019)

Pathway-based network analyses and candidate genes associated with Kashin-Beck disease
por: Zhang, Rongqiang, et al.
Publicado: (2019)

Total hip replacement in adult patients with severe Kashin-Beck disease of the hip
por: Tang, Xin, et al.
Publicado: (2016)

Correction: A study on atypical Kashin–Beck disease: an endemic ankle arthritis
por: Qi, Fang, et al.
Publicado: (2023)

WISP1 Is Involved in the Pathogenesis of Kashin-Beck Disease via the Autophagy Pathway
por: Li, Ping, et al.
Publicado: (2023)

UGA codon position-dependent incorporation of selenocysteine into mammalian selenoproteins
por: Turanov, Anton A., et al.
Publicado: (2013)

Mind the Gap: Genetic Manipulation of Basicranial Growth within Synchondroses Modulates Calvarial and Facial Shape in Mice through Epigenetic Interactions
por: Parsons, Trish E., et al.
Publicado: (2015)

Reliability and validity of the EQ-5D-3L for Kashin–Beck disease in China
por: Fang, Hua, et al.
Publicado: (2016)

Comparative Analysis of Gene Expression Profiles of Human Dental Fluorosis and Kashin-Beck Disease
por: Zhang, Qiang, et al.
Publicado: (2018)

Ecological analysis of Kashin-Beck osteoarthropathy risk factors in Tibet’s Qamdo City, China
por: Zha, Xinjie, et al.
Publicado: (2019)

Comparison of microRNA expression profiles of Kashin-Beck disease, osteoarthritis and rheumatoid arthritis
por: Wu, Wenhong, et al.
Publicado: (2017)

Association study of candidate genes for susceptibility to Kashin-Beck disease in a Tibetan population
por: Tai, Zhengfu, et al.
Publicado: (2017)

The molecular mechanism study of COMP involved in the articular cartilage damage of Kashin-Beck disease
por: Ma, Mei, et al.
Publicado: (2020)

Hydrochemical characteristics of surface waters and their relationships to the Kashin–Beck Disease in Longzi County, Tibet
por: Zha, Xinjie, et al.
Publicado: (2022)

Histone Deacetylase 3 Depletion in Osteo/Chondroprogenitor Cells Decreases Bone Density and Increases Marrow Fat
por: Razidlo, David F., et al.
Publicado: (2010)

Expression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocysteine 1 Associated Protein (Trnau1ap)
por: Mahdi, Yassin, et al.
Publicado: (2015)

Crystal structure of human selenocysteine tRNA
por: Itoh, Yuzuru, et al.
Publicado: (2009)

Tertiary structure of bacterial selenocysteine tRNA
por: Itoh, Yuzuru, et al.
Publicado: (2013)

Expression profile analysis of mycotoxin-related genes in cartilage with endemic osteochondropathy kashin-beck disease
por: Zhang, Feng, et al.
Publicado: (2012)

The expression of p-ATF2 involved in the chondeocytes apoptosis of an endemic osteoarthritis, Kashin-Beck disease
por: Han, Jing, et al.
Publicado: (2013)

Is It the Appropriate Time to Stop Applying Selenium Enriched Salt in Kashin-Beck Disease Areas in China?
por: Ning, Yujie, et al.
Publicado: (2015)

Serum levels of PIICP, PIIANP, and PIIBNP are decreased in patients with an endemic osteochondropathy, Kashin-Beck disease
por: Lian, Wei, et al.
Publicado: (2018)

Differential gene expression in articular cartilage between rheumatoid arthritis and endemic Kashin–Beck disease
por: Gao, Zongqiang, et al.
Publicado: (2019)

Comparison of the responsiveness of the WOMAC and the 12-item WHODAS 2.0 in patients with Kashin–Beck disease
por: Yang, Lei, et al.
Publicado: (2020)

Alterations in the gut microbiota and metabolite profiles of patients with Kashin-Beck disease, an endemic osteoarthritis in China
por: Wang, Xi, et al.
Publicado: (2021)

Computational identification of the selenocysteine tRNA (tRNA(Sec)) in genomes
por: Santesmasses, Didac, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_bkuk456ch2nd5vnn467dml7tk6