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Immature and Maturation-Resistant Human Dendritic Cells Generated from Bone Marrow Require Two Stimulations to Induce T Cell Anergy In Vitro

Immature dendritic cells (DC) represent potential clinical tools for tolerogenic cellular immunotherapy in both transplantation and autoimmunity. A major drawback in vivo is their potential to mature during infections or inflammation, which would convert their tolerogenicity into immunogenicity. The...

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Detalles Bibliográficos
Autores principales: Berger, Thomas G., Schulze-Koops, Hendrik, Schäfer, Michaela, Müller, Ester, Lutz, Manfred B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721636/
https://www.ncbi.nlm.nih.gov/pubmed/19680551
http://dx.doi.org/10.1371/journal.pone.0006645