New Aldehyde Tag Sequences Identified by Screening Formylglycine Generating Enzymes in Vitro and in Vivo

[Image: see text] Formylglycine generating enzyme (FGE) performs a critical posttranslational modification of type I sulfatases, converting cysteine within the motif CxPxR to the aldehyde-bearing residue formylglycine (FGly). This concise motif can be installed within heterologous proteins as a gene...

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Detalles Bibliográficos
Autores principales: Rush, Jason S., Bertozzi, Carolyn R.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721638/
https://www.ncbi.nlm.nih.gov/pubmed/18722427
http://dx.doi.org/10.1021/ja804530w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721638/
https://www.ncbi.nlm.nih.gov/pubmed/18722427
http://dx.doi.org/10.1021/ja804530w

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