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FoxM1 Is a General Target for Proteasome Inhibitors

Proteasome inhibitors are currently in the clinic or in clinical trials, but the mechanism of their anticancer activity is not completely understood. The oncogenic transcription factor FoxM1 is one of the most overexpressed genes in human tumors, while its expression is usually halted in normal non-...

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Detalles Bibliográficos
Autores principales: Bhat, Uppoor G., Halasi, Marianna, Gartel, Andrei L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721658/
https://www.ncbi.nlm.nih.gov/pubmed/19672316
http://dx.doi.org/10.1371/journal.pone.0006593