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Conservation of structure and activity in Plasmodium purine nucleoside phosphorylases

BACKGROUND: Purine nucleoside phosphorylase (PNP) is central to purine salvage mechanisms in Plasmodium parasites, the causative agents of malaria. Most human malaria results from infection either by Plasmodium falciparum (Pf), the deadliest form of the parasite, or by the widespread Plasmodium viva...

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Detalles Bibliográficos
Autores principales: Chaikuad, Apirat, Brady, R Leo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721837/
https://www.ncbi.nlm.nih.gov/pubmed/19575810
http://dx.doi.org/10.1186/1472-6807-9-42