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Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs

Sterols are constituents of the cellular membranes that are essential for their normal structure and function. In mammalian cells, cholesterol is the main sterol found in the various membranes. However, other sterols predominate in eukaryotic microorganisms such as fungi and protozoa. It is now well...

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Detalles Bibliográficos
Autores principales: de Souza, Wanderley, Rodrigues, Juliany Cola Fernandes
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721973/
https://www.ncbi.nlm.nih.gov/pubmed/19680554
http://dx.doi.org/10.1155/2009/642502