Knocking-Down Cyclin A(2) by siRNA Suppresses Apoptosis and Switches Differentiation Pathways in K562 Cells upon Administration with Doxorubicin

Cyclin A(2) is critical for the initiation of DNA replication, transcription and cell cycle regulation. Cumulative evidences indicate that the deregulation of cyclin A(2) is tightly linked to the chromosomal instability, neoplastic transformation and tumor proliferation. Here we report that treatmen...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xiaohui, Song, Yujun, Ren, Jinsong, Qu, Xiaogang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721982/
https://www.ncbi.nlm.nih.gov/pubmed/19684852
http://dx.doi.org/10.1371/journal.pone.0006665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721982/
https://www.ncbi.nlm.nih.gov/pubmed/19684852
http://dx.doi.org/10.1371/journal.pone.0006665

Ejemplares similares