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rna interference and micro rna –oriented therapy in cancer: rationales, promises, and challenges

The discovery that rna interference (rnai) and its functional derivatives, small interfering rnas (sirnas) and micro-rnas (mirnas) could mediate potent and specific gene silencing has raised high hopes for cancer therapeutics. The prevalence of these small (18–25 nucleotide) non-coding rnas in human...

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Detalles Bibliográficos
Autores principales: Duchaine, T.F., Slack, F.J.
Formato: Texto
Lenguaje:English
Publicado: Multimed Inc. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722055/
https://www.ncbi.nlm.nih.gov/pubmed/19672426