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rna interference and micro rna –oriented therapy in cancer: rationales, promises, and challenges
The discovery that rna interference (rnai) and its functional derivatives, small interfering rnas (sirnas) and micro-rnas (mirnas) could mediate potent and specific gene silencing has raised high hopes for cancer therapeutics. The prevalence of these small (18–25 nucleotide) non-coding rnas in human...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Multimed Inc.
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722055/ https://www.ncbi.nlm.nih.gov/pubmed/19672426 |