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CpG Methylation Controls Reactivation of HIV from Latency

DNA methylation of retroviral promoters and enhancers localized in the provirus 5′ long terminal repeat (LTR) is considered to be a mechanism of transcriptional suppression that allows retroviruses to evade host immune responses and antiretroviral drugs. However, the role of DNA methylation in the c...

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Detalles Bibliográficos
Autores principales: Blazkova, Jana, Trejbalova, Katerina, Gondois-Rey, Françoise, Halfon, Philippe, Philibert, Patrick, Guiguen, Allan, Verdin, Eric, Olive, Daniel, Van Lint, Carine, Hejnar, Jiri, Hirsch, Ivan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722084/
https://www.ncbi.nlm.nih.gov/pubmed/19696893
http://dx.doi.org/10.1371/journal.ppat.1000554