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Proteophosophoglycans Regurgitated by Leishmania-Infected Sand Flies Target the L-Arginine Metabolism of Host Macrophages to Promote Parasite Survival

All natural Leishmania infections start in the skin; however, little is known of the contribution made by the sand fly vector to the earliest events in mammalian infection, especially in inflamed skin that can rapidly kill invading parasites. During transmission sand flies regurgitate a proteophosph...

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Detalles Bibliográficos
Autores principales: Rogers, Matthew, Kropf, Pascale, Choi, Beak-San, Dillon, Rod, Podinovskaia, Maria, Bates, Paul, Müller, Ingrid
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722086/
https://www.ncbi.nlm.nih.gov/pubmed/19696894
http://dx.doi.org/10.1371/journal.ppat.1000555