Myocyte necrosis underlies progressive myocardial dystrophy in mouse dsg2-related arrhythmogenic right ventricular cardiomyopathy

Mutations in the cardiac desmosomal protein desmoglein-2 (DSG2) are associated with arrhythmogenic right ventricular cardiomyopathy (ARVC). We studied the explanted heart of a proband carrying the DSG2-N266S mutation as well as transgenic mice (Tg-NS) with cardiac overexpression of the mouse equival...

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Detalles Bibliográficos
Autores principales: Pilichou, Kalliopi, Remme, Carol Ann, Basso, Cristina, Campian, Maria E., Rizzo, Stefania, Barnett, Phil, Scicluna, Brendon P., Bauce, Barbara, van den Hoff, Maurice J.B., de Bakker, Jacques M.T., Tan, Hanno L., Valente, Marialuisa, Nava, Andrea, Wilde, Arthur A.M., Moorman, Antoon F.M., Thiene, Gaetano, Bezzina, Connie R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722163/
https://www.ncbi.nlm.nih.gov/pubmed/19635863
http://dx.doi.org/10.1084/jem.20090641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722163/
https://www.ncbi.nlm.nih.gov/pubmed/19635863
http://dx.doi.org/10.1084/jem.20090641

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