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S region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombination
Immunoglobulin class switch recombination is governed by long-range interactions between enhancers and germline transcript promoters to activate transcription and modulate chromatin accessibility to activation-induced cytidine deaminase (AID). However, mechanisms leading to the differential targetin...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722165/ https://www.ncbi.nlm.nih.gov/pubmed/19596805 http://dx.doi.org/10.1084/jem.20081678 |